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You are here: Home / Investigator Support / Pilot Funding
  • A clinician scientist and junior investigators set up a rheumatic disease epigenetics study

    Pilot Program


    One year of funding to generate preliminary data for national funding applications

 

PROGRAM GOALS

  • Identify and fund highly innovative ORDRCC Pilot Grants from junior ORDRCC investigators or established investigators with novel ideas in a new field of investigation
  • Provide career and scientific mentoring to Pilot Project investigators and applicants
  • Evaluate progress of projects and effectiveness of mentors and ensure that this program continues to provide key resources for outstanding scientific opportunities

 

ELIGIBLE APPLICANTS

  • Junior investigators who have independent research groups and no previous NIH R01
  • Established investigators with a completely new direction for their research group

 

HOW TO APPLY

A call for proposals is released every August.

 

Application requirements

A 3-page NIH-styled proposal for sections 1 and 2 (using NIH grant application forms):

  1. Specific Aims
  2. Research Strategy with Significance, Preliminary Data (if available), Innovation, and Approach
  3. References (does not count against page limits)
  4. NIH-style one year budget and justification
  5. NIH biosketch and other support
  6. IRB approval or pending application

 

Application review

The Internal Advisory Committee coordinates scientific review of applications based on:

  • Scientific merit
  • Degree of innovation
  • Potential to affect the field
  • Probability of success for future funding and scientific success
  • Quality of the proposal
  • Current funding status of the applicant

 

Evaluation

Six months into the award cycle, each funded investigator will provide a 1-2 page progress report to the respective mentoring committee. Pilot Investigators meet with the External Advisory Committee to discuss the project and career directions, and submit a final report on the project’s outcomes.

In addition, current and previous investigators submit annual impact information regarding publications, future support, career development, etc. These outcomes are crucial for the continued funding of this program.

 

PREVIOUS PILOT AWARD RECIPIENTS

  • Joel M. Guthridge, PhD: “Gene and functional analysis of LYN alleles associated with lupus”
  • Andrea L. Sestak, MD, PhD: “Investigation of candidate genes in SLE”
  • Courtney Montgomery, PhD: “Genetics of early lupus autoimmunity in African-Americans”
  • Sherry R. Crowe, PhD: “Influenza infection and autoimmunity”
  • Amr Sawalha, MD: “Genetic Association Studies in Behçet’s disease”
  • J. Shannon Maier-Moore, PhD: “Pathogenic monoclonal antibodies in Sjögren’s syndrome”
  • Melissa E. Munroe, MD, PhD: “Ascertaining molecular signatures of Active SLE”
  • Kenneth Smith, PhD: “Characterization of anti-phospholipid antibodies from patients with anti-phospholipid syndrome”
  • Eliza F. Chakravarty, MD: “Vaccination in rheumatoid arthritis”
  • Tim Griffin, PhD: “Cartilage Lipid Metabolism in Obesity and Osteoarthritis”
  • Mikhail Dozmorov, PhD: “H3K4me ½ histone methylation marks differences in Systemic Lupus Erythematosus”
  • Christopher Lessard, PhD: “Genomic Regulation of Chromosome 16q24.1 near IRF8 in Systemic Lupus Erythematosus”

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Study Recruitment

fp1 Clinical staff and facilities for regulatory support, recruitment, and study visits.

Human Phenotyping

fp2 High throughput -omics technologies for immune phenotyping in single cells, bulk samples, and tissues.

Rheumatic Disease Collections

fp3 Well characterized patient samples with associated clinical and experimental data

Additional Support

For questions about other ORDRCC resources, please e-mail us at ADI-Requests@omrf.org

Cite ORDRCC Support
Publications that used ORDRCC consultations, services, or resources should cite P30AR073750.

Oklahoma Rheumatic Disease Research Cores Center

At the Oklahoma Medical Research Foundation in Oklahoma City, OK

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MENU
  • Welcome
  • Leadership
  • Administrative Core
  • Cores
    • Clinical Characterization and Biorepository Core
    • Human Phenotyping Core
    • Request Services
  • Investigator Support
    • Center Investigators
    • Proposal Development
    • Pilot Funding
  • For Patients
    • Get Involved
    • Getting to the Clinic
  • Discoveries