ORDRCC

Welcome
Leadership
Administrative Core
Cores
Investigator Support
For Patients
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What we're about

Advancing prediction, prevention, and precision therapy for patients with rheumatic diseases
Who we are

Over 200 researchers spanning the basic, clinical, and analytical sciences
How we help

World-class core facilities and investigator support to drive groundbreaking research and launch distinctive careers
Why we care

Patients with rheumatic diseases need better tests and personalized treatments so they can live healthier, longer lives

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Extensive Cohort Collections

Our CAP-accredited biorepository manages some of the largest existing collections of SLE, Sjogren’s, RA, and osteoarthritis samples

Cutting Edge Methodologies

The Human Phenotyping Core offers single-cell technologies, including CyTOF, Spatial Transcriptomics, and scRNASeq

Clinical Research Expertise

A physician examines a patient's hand in an exam room — The Clinical Core assists with IRB approvals, study recruitment, and clinical research visits

Recent Publications

Evaluating Anti-CCL25 as a Therapeutic Strategy to Disrupt Foci Formation in a Spontaneous Murine Model of Sjögren's Disease September 27, 2025
Variants in the DDX6-CXCR5 autoimmune disease risk locus influence the regulatory network in immune cells and salivary gland May 30, 2025
Deep immunophenotyping reveals circulating activated lymphocytes in individuals at risk for rheumatoid arthritis March 17, 2025
Disease diagnostics using machine learning of B cell and T cell receptor sequences February 20, 2025
Association between antiphospholipid antibodies and diffuse alveolar haemorrhage risk in systemic lupus erythematosus: a systematic review and meta-analysis November 19, 2024
Reply October 17, 2024
Variants in the <em>DDX6-CXCR5</em> autoimmune disease risk locus influence the regulatory network in immune cells and salivary gland July 29, 2024

Cite ORDRCC Support
Publications that used ORDRCC consultations, services, or resources should cite P30AR073750.

Oklahoma Rheumatic Disease Research Cores Center

At the Oklahoma Medical Research Foundation in Oklahoma City, OK

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Welcome
Leadership
Administrative Core
Cores
Investigator Support
For Patients
- Get Involved
- Getting to the Clinic
Discoveries